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Blood, 1 December 2006, Vol. 108, No. 12, pp. 3635. This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Search for Related Content Related Collections Blood Work Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  BLOOD WORK Anemia and splenomegaly Figure 1.. A 29-year-old white male who visits the emergency room after an auto injury is noted to have mild anemia (hemoglobin level 111 g/L) and a palpable spleen tip. He has a number of laboratory tests drawn, including those for HIV, EB, CMV, and hepatitis. A hematology consultant sees him and asks, "Anyone in your family with anemia or an enlarged spleen?" He answers affirmatively. The peripheral smear shows a prominence of uniformly elliptical cells. Given the positive family history, the smear is indicative of hereditary elliptocytosis (HE). This relatively common hereditary hemolytic anemia is autosomal dominant in transmission. Most patients are not anemic because of a compensated hemolytic anemia. But approximately 10% have a mild degree of anemia and splenomegaly. The history and a review of the peripheral smear usually make the diagnosis. Neil Abramson, Baptist Cancer Institute   [View Larger Version of this Image (63K GIF file)]   The above image was first published in the ASH IMAGE BANK, a reference and teaching tool that is continually updated with new atlas images and images of case studies. For more information or to contribute to the Image Bank, visit ashimagebank.hematologylibrary.org. CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this? This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Search for Related Content Related Collections Blood Work Social Bookmarking                   What's this?

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