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Blood, Vol. 103, Issue 1, 242-251, January 1, 2004
Interleukin-6–dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family–independent survival pathway closely associated with Stat3 activation
Blood Brocke-Heidrich et al.
103: 242
Supplemental materials for: Brocke-Heidrich et al, Vol 103, Issue 1, 242-251
Files in this Data Supplement:
- Table S1. Microarray analysis of IL 6−regulated genes in INA-6 mutliple myeloma cells (XLS, 0.1 MB)
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INA-6 cells were cultured either in the presence of 1 ng/mL IL-6 or deprived of IL-6 for 12 h before restimulation with IL-6 for 1 h or 4 h. Expression patterns were studied using the Affymetrix U95A array. Two independent series of the experiment were carried out. Microarrays derived from IL-6−treated cells (experimental arrays) were compared with reference (ref.) arrays representing cells withdrawn from IL-6 for 12 h. Shown are those probe sets that report at least a 1.5-fold expression change in response to IL-6 addition to INA-6 cells.
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