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Blood, Vol. 104, Issue 1, 224-226, July 1, 2004
Artificial antigen-presenting constructs efficiently stimulate minor histocompatibility antigen–specific cytotoxic T lymphocytes
Blood Oosten et al.
104: 224
Supplemental materials for: Oosten et al, Vol 104, Issue 1, 224-226
Files in this Data Supplement:
- Document S1. Determination of optimal ligand densities (PDF, 48 KB)
- Figure S1. Optimization of aAPC-coating (PDF, 60 KB) -
Proliferation (A) and IFN-
 production (B) of HA-1–specific CTL clone 2.12 and HA-2–specific CTL clone 1.7 stimulated with aAPCs that were coated with various concentrations of specific ligand (x-axis) but without the costimulatory molecules CD80 and CD54. Proliferation (C) and IFN- production (D) of CTL clones 2.12 and 1.7 stimulated with aAPCs coated with the specific ligand in the absence of costimulatory molecules, with aAPCs additionally coated with CD80 or CD54, or with fully coated aAPCs (HLA-A2/mHag complexes, CD80, CD54).
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