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Blood, Vol. 104, Issue 5, 1435-1441, September 1, 2004
Acute lymphoblastic leukemia with TEL-AML1 fusion has lower expression of genes involved in purine metabolism and lower de novo purine synthesis
Blood Zaza et al.
104: 1435
Supplemental materials for: Zaza et al, Vol 104, Issue 5, 1435-1441
Files in this Data Supplement:
- Document 1. Expression of purine metabolism genes in TEL-AML1 ALL (PDF, 478 KB) -
The supplemental document contains additional information on the cases studied, analysis of the correlation between real-time RT-PCR, protein levels and Affymetrix gene chip signals, a graphical diagram of the purine metabolism pathway, unsupervised hierarchical clustering of patients based on gene expression patterns, and gene expression analysis that include an additional patient in whom the leukemia cells contain a disruption of the TEL gene due to a cryptic 3-way translocation.
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