SEARCH:   Advanced

Blood, Vol. 105, Issue 9, 3512-3520, May 1, 2005 This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef The threshold of gp130-dependent STAT3 signaling is critical for normal regulation of hematopoiesis Blood Jenkins et al. 105: 3512 Supplemental materials for: Jenkins et al, Vol 105, Issue 9, 3512-3520 Files in this Data Supplement: Figure S1. Dose-response curves of hematopoietic progenitor colony formation in response to IL-3 or SCF (PDF, 23 KB) - Colony formation of mutant gp130Y757F/Y757F (F/F) and wild-type gp130+/+ (+/+) bone marrow cells in semisolid agar containing the indicated concentrations of SCF (A) or IL-3 (B). Data are presented as percentage of maximum numbers of colonies emerging in cultures containing the highest concentration of cytokines. Figure S2. Intermediate phenotype in heterozygous gp130Y757F/+ (F/+) mice (PDF, 21 KB) - (A) Weights of spleen, thymus, and lymph nodes, and (B) platelet counts from gp130Y757F/Y757F mice, F/+, and and gp130+/+ littermates. Data are from 5 to 8 mice of each genotype and are expressed as the mean ± SD. *P < .05 versus data from gp130+/+ mice. Figure S3. Enhanced survival of gp130Y757F/Y757F hematopoietic cells (PDF, 23 KB) - Survival of unfractionated bone marrow and spleen cells in response to IL-11 (100 ng/mL). Equal numbers of cells were cultured over 5 days, and the number of viable cells was counted. Data from 3 separate experiments were pooled and are presented as the mean ± SD. *P < .05 versus data from the corresponding gp130+/+ cultures. This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef

	Copyright © 2009 by American Society of Hematology         Online ISSN: 1528-0020