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Blood, Vol. 105, Issue 9, 3686-3690, May 1, 2005 This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef The promyelocytic leukemia protein PML regulates c-Jun function in response to DNA damage Blood Salomoni et al. 105: 3686 Supplemental materials for: Salomoni et al, Vol 105, Issue 9, 3686-3690 Files in this Data Supplement: Figure S1. Cisplatin-induced apoptosis is reduced in Pml-/- MEFs (JPG, 64.6 KB) - Analysis of apoptosis in Pml+/+ and Pml-/- MEFs treated with 2.5 or 5.0 µg/mL cis-pt by subdiploid peak analysis. Average of 3 independent experiments ± SD is shown. Figure S2. c-Jun DNA-binding activity is impaired in Pml-/- MEFs (JPG, 57.8 KB) - Pml+/+ and Pml-/- MEFs were harvested 0 and 2 hours after UV irradiation (60 J/m2). Nuclear extracts were tested for DNA binding activity to a jun2 CRE site. Supershift experiments were performed by using antibodies against c-Jun and ATF-2. Sp1 binding activity was measured as control of loading. Data shown are representative of 3 independent experiments. Figure S3. Colocalization of P-c-Jun and PML is statistically significant (JPG, 261 KB) - Micrographs shown in Figure 5A were analyzed using the ImarisColoc software (Bitplane, Zurich, Switzerland). Statistical analysis is shown. This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef

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