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Blood, Vol. 106, Issue 1, 372-375, July 1, 2005
Association of klotho, bone morphogenic protein 6, and annexin A2 polymorphisms with sickle cell osteonecrosis
Blood Baldwin et al.
106: 372
Supplemental Tables and Figures for: Baldwin et al, Vol 106, Issue 1, 372-375
Files in this Data Supplement:
- Table S1. Assay design (XLS, 406 KB)
- Table S2. Comparison of patients with osteonecrosis (AVN) and without osteonecrosis (JPG, 119 KB)
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- Figure S1. Gene structure and SNP location in the KL, BMP and ANXA2 genes (JPG, 46 KB)
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Solid black boxes indicate exons within the gene. The hashed box in KL shows the location of an alternative exon and stop codon; solid arrows, the location of SNPs that are associated with osteonecrosis; open arrows, the location of SNPs we studied that were not associated with osteonecrosis; and gray diamonds, the location of retroviral LTRs within the KL gene.
- Figure S2. Linkage disequilibrium between SNPs typed in KL (JPG, 183 KB)
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Solid black cells indicate LD greater than 90% and gray cells greater than 75%. The boxes surrounding SNP numbers indicate those selected for haplotype analysis.
- Figure S3. Linkage disequilibrium between SNPs typed in ANXA2 (JPG, 113 KB)
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Solid black cells indicate LD greater than 90% and gray cells greater than 75%. The boxes surrounding SNP numbers indicate those selected for haplotype analysis.
- Figure S4. Linkage disequilibrium between SNPs typed in BMP (JPG, 113 KB)
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Solid black cells indicate LD greater than 90% and gray cells greater than 75%. The boxes surrounding SNP numbers indicate those selected for haplotype analysis.
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