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Blood, Vol. 106, Issue 7, 2356-2362, October 1, 2005
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The TUBB1 Q43P functional polymorphism reduces the risk of cardiovascular disease in men by modulating platelet function and structure
Blood Freson et al. 106: 2356

Supplemental materials for: Freson et al, Vol 106, Issue 7, 2356-2362

Files in this Data Supplement:

  • Figure S1. Platelet morphology (PDF, 604 KB) - Electron microscopy of platelets (original magnification, × 22,500) of a normal individual and four heterozygous 1-tubulin Q43P carriers, showing cytoplasmic inclusions composed of smooth endoplasmic reticulum and abnormal membrane complexes (arrow). Note also the organelle-free zones in some platelets (arrowhead). The parent of patient 5 has some giant platelets.



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