|
|
Blood, Vol. 107, Issue 5, 2090-2093, March 1, 2006
Distinct gene expression patterns in chronic lymphocytic leukemia defined by usage of specific VH genes
Blood Kienle et al.
107: 2090
Supplemental materials for: Kienle et al
Files in this Data Supplement:
- Table S1 (PDF, 19.7 KB) -
Distribution of Binet stage (absolute numbers and percentage), median age (years), gender, and of the high risk genomic aberrations 11q- or 17p- (percentage) within the a) non-purified (n=69) and b) purified cohort (n=54) and the VH subgroups under study.
- Table S2. Forward and reverse primers designed for SYBR Green detection (PDF, 17.7 KB)
- Table S3. VH mutation status and CDR3 composition of the V3-21 cases (PDF, 16.1 KB) -
All rearrangements were productive. ° Non-CD19 purified cohort, * purified cohort.
- Table S4 (PDF, 21.2 KB) -
Comparison of candidate gene expression between mutated V3-21 vs. unmutated V3-21 cases (Wilcoxon rank-sum test statistics for pairwise comparisons; p-values are not corrected for multiple comparisons). Fold expression changes are shown with the corresponding 95% confidence intervals (LCL/UCL: lower/upper confidence limit). ° Results from the purified cohort.
- Table S5. VDJ structure of the V1-69 cases (PDF, 22.1 KB) -
° Non-CD19 purified cohort, * purified cohort. N.a.: not assigned. All rearrangements were productive.
- Table S6 (PDF, 21.3 KB) -
Comparison of candidate gene expression between the subgroups V1-69 vs. V3-21 (Wilcoxon rank-sum test statistics for pairwise comparisons; p-values are not corrected for multiple comparisons). Fold expression changes are shown with the corresponding 95% confidence intervals (LCL/UCL: lower/upper confidence limit). ° Results from the purified cohort.
|
|
