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Blood, Vol. 107, Issue 5, 1896-1902, March 1, 2006
Heterodimerization of FGF-receptor 1 and PDGF-receptor- Files in this Data Supplement: A. Mitogenic effect of FGF-2 (10 ng/ml) was strongly and significantly inhibited in the presence of PDGF-BB (10 ng/ml). The effect of PDGF-BB is dose-dependent and is evident at 10 ng/ml. The experiment, carried out as reported in the legend of Fig. 5, was performed onto SK-Mel 110 human melanoma cells. FRET signal is evident between FGF-R1 and PDGF-R alpha molecules, in section B3.
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