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Blood, Vol. 107, Issue 7, 2889-2894, April 1, 2006 This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status Blood Thorsélius et al. 107: 2889 Supplemental materials for: Thorsélius et al, Vol 107, Issue 7, 2889-2894 Files in this Data Supplement: Table S1. Characteristics of Ig gene rearrangements in VH3-21+ CLL (PDF, 175 KB) - Gene usage, mutation frequency, and functionality of VH and VL rearrangements in VH3-21+ patients with known (A) and unknown (B) / expression Table S2. κ-deleting element rearrangements in λ-expressing VH3-21+ CLL patients (PDF, 46 KB) Figure S1. Schematic view of possible rearrangements involving the κ-deleting element (KDE) (JPG, 23.6 KB) - The Vκ gene can be inactivated by 2 possible alternate rearrangements of the KDE; it can rearrange to either (A) a recombination signal sequence (RSS) located close to the Vκ gene segments, deleting the whole Vκ gene including VκJκ joining and the constant region (Cκ), or (B) the intron RSS, thereby deleting the Cκ region. This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef

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