SEARCH:   Advanced

Blood, Vol. 107, Issue 12, 4898-4906, June 15, 2006 This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation Blood Hoelbl et al. 107: 4898 Supplemental materials for: Hoelbl et al Files in this Data Supplement: Figure S1. Expression of N-terminally truncated Stat5a/b in Stat5a/bΔN/ΔN mice (JPG, 48.5 KB) - Two Stat5a/b+/+, eight Stat5a/bΔ/+ and eight Stat5a/bΔN/ΔN Ab-MuLV transformed cell lines were examined for Stat5a/b expression by Western Blot analysis. Figure S2. Comparable numbers of LT-HSCs and ST-HSCs in S5null/null fetal livers and controls (JPG, 103 KB) - (A) Percentages of lin—/c-kit+/sca-1+ cells in Stat5a/b+/+ and Stat5a/bnull/null fetal livers. (B) Percentages of LT-HSCs (CD34—) and ST-HSCs (CD34+) gated on lin—/c-kit+/sca-1+ cells. Figure S3. In vitro B cell development of fetal liver cells on an irradiated MEF feeder layer (JPG, 108 KB) - Stat5a/bnull/+ (n=5) and Stat5a/bnull/null (n=4) fetal liver cells (ED 14) were co-cultivated on an irradiated (15Gy) MEF feeder layer in the presence of IL-7 (10 ng/ml). Generation of pro B cell stages (fraction A-C) and pre B cells (fraction D) is depicted. Figure S4. Comparable disease patterns in Rag2—/— mice transplanted with either Stat5a/b+/+, Stat5a/bnull/+ and Stat5a/bnull/null/Stat5a/b+/+ (ratio 1:4) Ab-MuLV transformed bone marrow cells (JPG, 123 KB) - (A) Hematoxiline/eosine-stained histological sections of livers and spleens (magnification: 100×). (B) Spleen weights and flow cytometric analysis of leukemic spleen and bone marrow infiltration (CD19+/CD43+ cells) of sick Rag2—/— mice. This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef

	Copyright © 2009 by American Society of Hematology         Online ISSN: 1528-0020