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Blood, Vol. 108, Issue 3, 936-942, August 1, 2006

Structural basis for platelet collagen responses by the immune-type receptor glycoprotein VI
Blood Horii et al.
108: 936
Supplemental materials for: Horii et al, Vol 108, Issue 3, 936-942
Files in this Data Supplement:
- Figure S1. Sequence alignment of GPVI and other LRC receptors (JPG, 78.2 KB)
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Included are the GPVI CBD, D1 and D2 of the LIR-1 ectodomain, and the full D1 to D2 ectodomains of p58 KIR and Fc RI. The 11-residue deletion in GPVI is highlighted in yellow. Highly conserved prolines found between the A and A′ strands of LRC receptors are shown in bold and are red if they are found in the cis conformation and blue if found in the trans conformation. A schematic of the GPVI structure is shown above the sequence, labeled according to strand, helix, or polyproline type II helix (pp).
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