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Blood, Vol. 108, Issue 7, 2339-2348, October 1, 2006
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Gene expression of tumor angiogenesis dissected: specific targeting of colon cancer angiogenic vasculature
Blood van Beijnum et al. 108: 2339

Supplemental materials for: van Beijnum et al

Files in this Data Supplement:

  • Document 1. Supplemental materials and methods (PDF, 26.1 KB)

  • Figure S1. Hierarchical clustering of differential gene expression patterns in TEC, NEC, PLEC and HUVEC (JPG, 34.8 KB) -

    Hierarchical clustering analysis of expression ratios of the entire SSH repertoire. The dendrogram represents the results of hierarchical clustering analysis based on similarities in gene expression patterns of the different comparisons indicated to the right of the clustered image maps. Expression ratios are color-coded as indicated on the far right and shown for the indicated comparisons. Bars at the bottom indicate clustered regions containing the genes that confer a tumor “signature” to EC (TAGs). The dendrogram at the left is an indicator of overall correlation between the comparisons shown in the rows. Note that differential gene expression during physiological angiogenesis (PLEC vs NEC) is most closely related to differential gene expression in activated vs quiescent HUVEC (H+ vs H-).





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