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Blood, Vol. 109, Issue 8, 3521-3528, April 15, 2007

Generation of activation-specific human anti- Mß2 single-chain antibodies as potential diagnostic tools and therapeutic agents
Blood Eisenhardt et al.
109: 3521
Supplemental materials for: Eisenhardt et al, Vol 109, Issue 8, 3521-3528
Files in this Data Supplement:
- Video 1. Nonstimulated monocytes flowing over a fibrinogen matrix without MAN-1 antibody (MOV, 3.42 MB)
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The clip shows venous flow conditions in the beginning. After approximately 30 seconds, arterial flow is applied.
- Video 2. PMA-stimulated monocytes flowing over a fibrinogen matrix without MAN-1 antibody (MOV, 3.44 MB)
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The clip shows venous flow conditions in the beginning. After approximately 30 seconds, arterial flow is applied.
- Video 3. Nonstimulated monocytes flowing over a fibrinogen matrix after preincubation with MAN-1 antibody (MOV, 3.44 MB)
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The clip shows venous flow conditions in the beginning. After approximately 30 seconds, arterial flow is applied.
- Video 4. PMA-stimulated monocytes flowing over a fibrinogen matrix after preincubation with MAN-1 antibody (MOV, 3.43 MB)
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The clip shows venous flow conditions in the beginning. After approximately 30 seconds, arterial flow is applied.
- Video 5. Nonstimulated monocytes flowing over a fibrinogen matrix after preincubation with a blocking anti-CD11b antibody (MOV, 3.41 MB)
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The clip shows venous flow conditions in the beginning. After approximately 30 seconds, arterial flow is applied.
- Video 6. PMA-stimulated monocytes flowing over a fibrinogen matrix after preincubation with a blocking anti-CD11b antibody (MOV, 3.41 MB)
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The clip shows venous flow conditions in the beginning. After approximately 30 seconds, arterial flow is applied.
REFERENCES
1. O’Toole TE, Katagiri Y, Faull RJ, et al. Integrin cytoplasmic domains mediate inside-out signal transduction. J Cell Biol. 1994;124:1047-1059. 2. Peter K, O’Toole TE. Modulation of cell adhesion by changes in alpha L beta 2 (LFA-1, CD11a/CD18) cytoplasmic domain/cytoskeleton interaction. J Exp Med. 1995;181:315-326.
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