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Blood, Vol. 109, Issue 3, 1095-1102, February 1, 2007

Annexin-1 modulates T-cell activation and differentiation
Blood D'Acquisto et al.
109: 1095
Supplemental materials for: D’Acquisto et al, Vol 109, Issue 3, 1095-1102
Files in this Data Supplement:
- Figure S1. Effect of native or denatured hrAnx-A1 on T-cell activation (PDF, 17 KB) -
(A) Murine naïve lymph nodes T cells were stimulated with 1.25 µg/ml of anti-CD3/CD28 in absence or presence of 600nM of native (Anx-A1) or denatured (dAnx-A1) hrAnx-A1 for 24 h and then pulsed with 3H-thymidine to measure cell proliferation. (B) IL-2 production from primary murine naïve lymph nodes T cells stimulated with anti-CD3/CD28 (1.25 µg/ml) in absence or presence of 600nM native or denatured hrAnx-A1 for 24 h. In all the experiments values are mean ± S.E. of n=4-5 mice. **P<0.01.
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