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Blood, Vol. 110, Issue 1, 151-160, July 1, 2007
Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood
Blood Nagano et al.
110: 151
Supplemental materials for: Nagano et al, Volume 110, Issue 1, 151-160
Files in this Data Supplement:
- Figure 1. Alde-low EPCs were curative of ischemic tissue in nude mice (JPG, 40.0 KB)
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(A) Skin incisions were created on the dorsal surfaces of BALB/c nu/nu mice, and PBS alone, HUVECs, Alde-high EPCs, or Alde-low EPCs were injected (photographs/each condition). The effectiveness of ECs to recover tissue from ischemia was examined on day 7 following surgery without cyclosporin A treatment. (B) The necrotic regions in the 4 types of mice (n = 3) were measured. Note that the area of necrosis was smallest in the mice injected with Alde-low EPCs. Gray bar indicates PBS; striped bar, HUVECs; black bar, Alde-high EPCs; and white bar, Alde-low EPCs. **P < .01.
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