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Blood, Vol. 110, Issue 13, 4406-4416, December 15, 2007

The TCL1 oncoprotein inhibits activation-induced cell death by impairing PKC and ERK pathways
Blood Despouy et al.
110: 4406
Supplemental material for: Despouy et al
Files in this Data Supplement:
- Figure S1. (PDF, 206 KB) -
A) Jurkat-C and Jurkat-TCL1 were stimulated by UCHT1 for 10min and PKC was then analyzed by immunofluorescence using an anti-PKC (Cy3 - yellow). Representative images out of the three independent experiments are shown. B) Jurkat-C and Jurkat-TCL1 were stimulated by UCHT1 for 10min and phospho-AKT was analyzed by immunofluorescence using an anti-phospho-AKT (Cy3) with a counter-staining with DAPI (blue). Representative images out of three independent experiments are shown. C) PBMCs and T-PLL cells (TP22 and TP15) were stimulated by UCHT1 for 10min and PKC was analyzed by immunofluorescence using an anti-PKC (Cy3). Representative images out of two independent experiments are shown. D) PBMCs and T-PLL cells (TP22 and TP15) were stimulated by UCHT1 for 10min and P-AKT was analyzed by immunofluorescence using an anti-phospho-AKT (Cy3) with a counter-staining with DAPI. Representative images out of two independent experiments are shown.
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