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Blood, Vol. 110, Issue 1, 116-124, July 1, 2007
Abnormal hematopoiesis in Gab2 mutant mice
Blood Zhang et al.
110: 116
Supplemental materials for: Zhang et al, Vol 110, Issue 1, 116-124
Files in this Data Supplement:
- Figure S1. Impaired pERK and pS6, but not pSTAT5, response to IL-3 in freshly isolated Gab2–/– lineage-negative/low BM cells (JPG, 690 KB)
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Bone marrow cells were stimulated with IL-3 (0, 5, 15, and 30 minutes) immediately after isolation (ie, without starvation). (A) The level of phosphorylated ERK, S6, and STAT5 was determined in WT and Gab2–/– BM cells with high expression of c-Kit and low expression of lineage markers. (B) The levels of phosphorylated ERK, S6, and STAT5 were also analyzed in all cells with low expression of lineage markers but without respect to c-Kit expression level.
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