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Blood, Vol. 110, Issue 5, 1429-1438, September 1, 2007
Identification of genomic classifiers that distinguish induction failure in T-lineage acute lymphoblastic leukemia: a report from the Children's Oncology Group
Blood Winter et al.
110: 1429
Supplemental materials for Winter et al, Vol. 110, Issue 5, 1429-1438
Files in this Data Supplement:
- Figure S1. Intersection union testing of genes downregulated between IF patients and drug-resistant cell lines (JPG, 82 KB)
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Differential expression of 9 genomic classifiers (7 genes) that were down-regulated in intersection union testing between IF patients and drug-resistant cell lines. *Indicates multiple probes identified for the same gene (LAT and ANXA2).
- Figure S2. Box-plot distributions for 9 genomic classifiers down-regulated for IF patients and T-ALL cell lines with resistance to DNR or ASP (JPG, 88.9 KB)
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(A) 201590_×_at (EST 3902323), (B) 202954_at (UBE2C), (C) 209881_s_at (LAT), (D) 210427_×_at (ANXA2), (E) 211005_at (LAT), (F) 213060_s_at (CHI3L2), (G) 213503_×_at (3902323), (H) 223307_at (CDCA3) and (I) 230493_at (FLJ20489). These data show differential expression in genes with shared downregulation in the IF cohort, as compared to the RE and CCR subsets.
REFERENCE
1. Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U, Speed TP. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics. 2003(2):249-64.
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