Figure S2. 2B4 inhibits NK LAK production of IFN-γ (PDF, 10.7 KB) -
NK cells from perforin KO mice were activated with IL-2 in vitro for 3 days. The NK LAK cells were recultured at equal quantities in media containing FcR block with or without anti-2B4 or anti-CD48 blocking antibodies. After 24 hours in culture with blocking antibodies, supernatant was collected and analyzed for IFN- levels by ELISA assay. The data is representative of 6 independent experiments.