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Blood, Vol. 110, Issue 10, 3682-3690, November 15, 2007 This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef Essential role for Rap1 GTPase and its guanine exchange factor CalDAG-GEFI in LFA-1 but not VLA-4 integrin–mediated human T-cell adhesion Blood Ghandour et al. 110: 3682 Supplemental materials for: Ghandour et al Files in this Data Supplement: Figure S1. SDF-1α induces adhesion and polarization on ICAM-1 and VCAM-1 (JPG, 60.6 KB) - SDF-1-dependent cell adhesion and polarization on ICAM-1 and VCAM-1 under shear flow conditions. T cell adhesion and polarization were observed under unstimulated conditions, but was significantly induced by SDF-1. * P < 0.05, n=3 independent experiments. Figure S2. Effect of PKC inhibitors on Rap1 activation (JPG, 44.2 KB) - Inhibition of PKC by 20 nM Gö 6976 increases the levels of active Rap1 following SDF-1 stimulation (upper panel), whereas it prevented Rap1 activation following PMA stimulation (lower panel). Gö 6850 or Gö 6976 treatment alone (upper panel) had no effect on levels of GTP-loaded Rap in unstimulated cells. This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef

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