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Blood, Vol. 111, Issue 2, 767-775, January 15, 2008
Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome
Blood Kirsammer et al.
111: 767
Supplemental material for: Kirsammer et al
Files in this Data Supplement:
- Document 1. Supplemental methods (PDF, 13 KB)
- Table S1. Chromosome 21 gene orthologs on the Ts65Dn segmental Trisomy (PDF, 32 KB) -
From Olson LE, Richtsmeier JT, Leszl J, Reeves, RH. A chromosome 21 critical region does not cause specific Down syndrome phenotypes. Science. 2004;306:687-690. C indicates highly conserved genes; MC indicates minimally conserved genes.
- Table S2. Complete blood counts in Ts65Dn mice and euploid controls (PDF, 80 KB) -
Values listed are average ± SEM.
- Table S3. Peripheral blood folate levels are not significantly altered between Ts65Dn and controls (PDF, 12 KB) -
Values listed are average ± SEM.
- Table S4. Complete blood counts of recipients transplanted with Ts65Dn bone marrow (Ts65Dn) or euploid control bone marrow (control) (PDF, 63 KB) -
Values listed are average ± SEM. * indicates p<0.05; **indicates p<0.005.
- Figure S1. Long term survival is compromised in Ts65Dn bone marrow transplant recipients (PDF, 121 KB) -
A) Recipients of Ts65Dn and control bone marrow demonstrate substantial engraftment as evidenced by CD45.2 expression on peripheral blood cells. B) Survival curves of transplant recipient mice.
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