SEARCH:   Advanced

Blood, Vol. 111, Issue 2, 846-855, January 15, 2008 This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells Blood Longo et al. 111: 846 Supplements for: Longo et al Files in this Data Supplement: Figure S1. Nucleofection of CLL B-cells with control pCDNA3, myr.Akt or c.a.MEK2 mRNA (PDF, 76 KB) - The levels of phospho-Akt, HA-tagged MEK2, Mcl-1 and XIAP were investigated 48 hours after nucleofection with the indicated mRNAs. Actin was used as a loading control. Figure S2. Evaluation of cytotoxicity induced by the nucleofection procedure (PDF, 17KB) - (A) CLL cells were transfected with control mRNA and their viability was compared with the viability of untransfected cells after 48 hours. (B) The effect of mRNA transfection was evaluated by comparing viability of CLL cells transfected with or without control mRNA. Viability was assessed after 48 hours by Annexin V/PI staining. This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef

	Copyright © 2009 by American Society of Hematology         Online ISSN: 1528-0020