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Blood, Vol. 111, Issue 5, 2527-2537, March 1, 2008
Prognostic relevance of FLT3-TKD mutations in AML: the combination matters—an analysis of 3082 patients
Blood Bacher et al.
111: 2527
Supplemental materials for: Bacher et al
Files in this Data Supplement:
- Figure S1. Establishment and comparison of the melting curve analysis assay that was used for the screening in this study (PDF, 72.9 KB) -
(A) conventional restriction digest analysis as described before. (B) melting curve analysis.
- Figure S2 (PDF, 106 KB) -
(A) Overall survival and (B) event free survival of FLT-TKD-wiltdtpye (FLT-wt) versus FLT3-TKD mutated cases (FLT3-TKDmut) in all case. (C) Overall survival and (D) event free survival of FLT-TKD-wiltdtpye (FLT-wt) versus FLT3-TKD mutated cases (FLT3-TKDmut) in all case excluding FLT3-LM mutated. (E) Overall survival and (F) event free survival of FLT-TKD-wiltdtpye (FLT-wt) versus FLT3-TKD mutated cases (FLT3-TKDmut) in all case restricted to de novo AML.
- Figure S3 (PDF, 102 KB) -
(A) overall survival and (B) event free survival of FLT3-TKD-wiltdtpye (FLT3-wt) versus FLT3-TKD mutated cases (FLT3-TKDmut) in normal karyotype. (C) overall survival and (D) event free survival of FLT3-TKD-wiltdtpye (FLT3-wt) versus FLT3-TKD mutated cases (FLT3-TKDmut) in normal karyotype excluding cases with FLT3-LM. (C) overall survival and (D) event free survival of FLT3-TKD-wiltdtpye (FLT3-wt) versus FLT3-TKD mutated cases (FLT3-TKDmut) in normal karyotype excluding cases with FLT3-LM restricted to de novo AML.
- Figure S4 (PDF, 82.1 KB) -
(A) overall survival and (B) event free survival of FLT-TKD-wiltdtpye (FLT3-wt) versus FLT3-TKD mutated cases (FLT3-TKDmut) in the intermediate karyotype group. (C) overall survival and (D) event free survival of FLT-TKD-wiltdtpye (FLT3-wt) versus FLT3-TKD mutated cases (FLT3-TKDmut) in the intermediate karyotype group excluding cases with FLT3-LM.
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