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Blood, Vol. 112, Issue 1, 56-63, July 1, 2008
Guanine exchange factor RalGDS mediates exocytosis of Weibel-Palade bodies from endothelial cells
Blood Rondaij et al.
112: 56
Supplemental materials for: Rondaij et al
Files in this Data Supplement:
- Figure S1. Expression of RalGDS or RalA induce filopodia formation in endothelial cells (JPG, 60.3 KB)
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Confocal images of HUVEC expressing GFP, GFP-RalA or GFP-RalGDS. After cells had grown for 48 hours on glass coverslips, F-actin was visualized by immunofluorescence using Alexa568-conjugated phalloidin (red). Lower panels show magnifications of the areas within the boxes in the corresponding upper panels. Bars correspond to 10 µm. Expression of GFP-RalA and GFP-RalGDS induced the formation of filopodia reminiscent of RalA activation (arrows).
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