|
|
Blood, Vol. 111, Issue 3, 1248-1256, February 1, 2008
Application of high-throughput screening to identify a novel  IIb-specific small- molecule inhibitor of IIbβ3-mediated platelet interaction with fibrinogen
Blood Blue et al.
111: 1248
Supplemental materials for: Blue et al
Files in this Data Supplement:
- Video 1. Surface representation of compound 1 docked into αIIbβ3 (MPG, 2.33 MB)
-
The surface representation (1.4 Å probe radius) for the ligand binding site of  IIb 3 with docked compound 1 is shown. Residue character is indicated by the following color designations: blue (basic), red (acidic), white (aliphatic), cyan (aromatic), green (polar, mainly residues containing hydroxyl groups).
- Video 2. Surface representation of compound 1 docked into αVβ3 (MPG, 2.32 MB)
-
The surface representation (1.4 Å probe radius) for the ligand binding site of IIb3 with docked compound 1 is shown. Residue character is indicated by the following color designations: blue (basic), red (acidic), white (aliphatic), cyan (aromatic), green (polar, mainly residues containing hydroxyl groups).
|
|
