SEARCH:   Advanced

Blood, Vol. 110, Issue 13, 4175-4178, December 15, 2007 This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef Locus control region elements HS1 and HS4 enhance the therapeutic efficacy of globin gene transfer in β-thalassemic mice Blood Lisowski and Sadelain 110: 4175 Supplemental material for: Lisowski and Sadelain Files in this Data Supplement: Document 1. Supplemental materials and methods (PDF, 73.4 KB) Figure S1. Quantitative analysis and comparison of vector output in vivo at the mRNA and protein levels, with and without normalization to VCN (JPG, 43.6 KB) - (A) Correlation between human -globin transgene expression on RNA level (Hu/Hu+Mu) and Hb. Hb level was obtained by subtracting Th3/+ Hb ((Figure 2D) Th3/+ = 89 g/L) from total Hb level for each animal and corroborated by cellulose acetate gel electrophoreses (data not shown). See inset for color-coding. (B) Hemoglobin produced, normalized to vector copy (Hb/VCN) for each vector tested. Error bars represent SD; n indicates number of animals in each group. This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef

	Blood Online is supported in part by Genentech BioOncology and Biogen Idec
	Copyright © 2008 by American Society of Hematology         Online ISSN: 1528-0020