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Blood, Vol. 111, Issue 12, 5672-5682, June 15, 2008 This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef Leukemogenic mechanisms and targets of a NUP98/HHEX fusion in acute myeloid leukemia Blood Jankovic et al. 111: 5672 Supplemental materials for: Jankovic et al Files in this Data Supplement: Table S1. Oligonucleotide primers used for target validation by quantitative RT-PCR (PDF, 935 KB) Table S2. List of genes with significant differential expression in NUP98/HHEX transduced primary murine bone marrow (PDF, 1.45 MB) Table S3. List of genes with significant differential expression in NUP98/HOXA9 transduced primary murine bone marrow (PDF, 3.46 MB) Figure S1. Schematic map of the NUP98/HHEX isoforms resulting from t(5;10)(q23;p15) (JPG, 47.6 KB) - Figure S2. NUP98/HHEX ΔGLFG mutants (JPG, 87.1 KB) - (A) Schematic representation of NUP98/HHEX GLFG mutants analyzed in serial replating assays. (B) Serial replating assay of bone marrow cells transduced with NUP98/HHEX (WT) and NUP98/HHEX GFLG-deletion mutants. (C) Transient expression of NUP98/HHEX GFLG mutants in 293T cells. Figure S3. Immunoglobulin heavy-chain rearrangements were analyzed by PCR analysis (JPG, 44.7 KB) - Genomic DNA (100ng) from leukemic cells from 4 animals transplanted with NUP98/HHEX expressing bone marrow as analyzed by PCR using 3 degenerate primers (DFS, DQ52, JH4). Rearranged bands were found in all 4 samples. Tail DNA and normal spleen DNA (Balb/C) served as controls. All samples contained between 85 and 95% tumor cells, One sample was reanalyzed after FACS-sorting for EYFP+ (marked as #1S). This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef

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