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Blood, Vol. 111, Issue 3, 1665-1676, February 1, 2008 This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef Lentiviral (HIV)-based RNA interference screen in human B-cell receptor regulatory networks reveals MCL1-induced oncogenic pathways Blood Ruiz-Vela et al. 111: 1665 Supplemental materials for: Ruiz-Vela et al Files in this Data Supplement: Table S1. List of human gene targets (PDF, 29.4 KB) - Nucleotide sequences (19 ntd long) located in the open reading frame (ORF) of the target genes were selected using the SIDE software (http://side.bioinfo.ochoa.fib.es). Table S2. List of survival index (SI) values calculated for each individual shRNAi clone (PDF, 54.3 KB) - SI denotes a ratio between survival in GFP− and GFP+ population upon BCR cross-linking as indicated in Figure 2b. Percentage of GFP positive cells for each transduction denotes transduction efficiency. Table S3. List of genes modulated by enforced MCL1 expression in B-NHL cells (PDF, 51.1 KB) - Unsupervised analysis of the genes showed 468 human genes differentially expressed in both (RAMOS RA-1 and Z-138) cell types by MCL1 over-expression using a Log2 Cy-5/ Cy-3 cut-off= 0.5. Table S4. List of canonical pathways activated by enforced MCL1 expression (PDF, 34.5 KB) - Canonical pathways up-regulated by MCL1 were analyzed using Ingenuity Systems IPA 5.0 database. Table S5. List of canonical pathways repressed by enforced MCL1 expression (PDF, 31.8 KB) - Canonical pathways down-regulated by MCL1 were analyzed using Ingenuity Systems IPA 5.0 database. This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef

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