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Blood, Vol. 111, Issue 7, 3701-3713, April 1, 2008
Cooperative signaling through the signal transducer and activator of transcription 3 and nuclear factor- B pathways in subtypes of diffuse large B-cell lymphoma
Blood Lam et al.
111: 3701
Supplemental materials for: Lam et al
Files in this Data Supplement:
- Document 1. Supplemental materials and methods (PDF, 18 KB)
- Figure S1. Gene expression profiles of DLBCL cell lines (JPG, 193 KB)
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ABC DLBCL and GCB DLBCL cell lines and tumor samples were profiled for gene expression using Affymetrix U133plus arrays. Shown is the relative expression of genes that were differentially expressed between two lymphoma subgroups (p<0.001; mean fold difference > 1.5 fold) and that were differentially expressed between lymphoma subgroup cell lines (mean fold difference > 2 fold). In each panel, expression levels in tumor samples and cell lines were separately median centered.
- Figure S2. Downregulation of BCL-2 mRNA expression by IL-10 (JPG, 64.6 KB)
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Gene expression pattern of BCL-2 mRNA in OCI-Ly3 cells treated with IL-10 (50ng/ml) for 1-, 3-, 6-, 24-, and 48-hours. Results are shown as BCL-2 mRNA levels in IL-10-treated cells, log2 normalized to untreated levels.
- Table S1. Fig1a Ly310 iIKBSR database (XLS, 4.82 MB)
- Table S2. Fig2a Ly10 IL6 database (XLS, 2.09 MB)
- Table S3. Fig2b Ly3 IL10 database (XSL, 3.74 MB)
- Table S4. Fig2e Ly10 siSTAT3 database (XLS, 2.87 MB)
- Table S5. Fig4a ABC STAT3diffgenes (XLS, 1.62 MB)
- Table S6. Fig4c ABCsign ABCGCB DB (XLS, 118 KB)
- Table S7. Fig4c STAT3sign ABCGCB DB (XLS, 73.5 KB)
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