|
|
Blood, Vol. 111, Issue 5, 2816-2824, March 1, 2008
Potentially oncogenic B-cell activation–induced smaller isoforms of FOXP1 are highly expressed in the activated B cell–like subtype of DLBCL
Blood Brown et al.
111: 2816
Supplemental materials for: Brown et al.
Files in this Data Supplement:
- Figure S1. FOXP1 isoform expression in breast and prostate cell lines (PDF, 112 KB) -
Western blotting of seven breast and three prostate cancer cell lines using the JC12 antibody, demonstrating stronger expression of the smaller FOXP1 isoforms than the full length protein in the MDA-MB-231 cell line. However, the smaller isoforms in MDA-MB-231 are expressed at much lower levels than are observed in the OCI-Ly3 ABC-like DLBCL cell line indicated on the far left. The blot was re-probed with anti-actin as a loading control.
- Figure S2. Analysis of FOXP1 isoforms in normal tonsil (PDF, 143 KB) -
Western blotting of normal tonsil with the JC12 antibody detected predominantly the full-length protein. As in naive B cells, the smaller of the two lower molecular weight FOXP1 isoforms was also observed at low levels in normal tonsil.
| |
