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Blood, Vol. 112, Issue 4, 1472-1481, August 15, 2008
Leukocyte trafficking in a mouse model for leukocyte adhesion deficiency II/congenital disorder of glycosylation IIc
Blood Yakubenia et al.
112: 1472
Supplemental materials for: Yakubenia et al
Files in this Data Supplement:
- Figure S1. AAL-binding to GR-1+ leukocytes (JPG, 61.6 KB)
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Binding of fucose-specific AAL to Gr-1 positive leukocytes from Slc35c1bm−/− mice (thin line in upper panel), Slc35c1−/− mice (thin line in lower panel), and littermate control mice (bold line in both panels) was analyzed by flow cytometry. Leukocytes were incubated with APC-labeled mAb Gr-1 binding to the Ly-6 antigen and with PE-conjugated streptavidin in combination with biotinylated AAL or PE-conjugated streptavidin alone (thin line with filled area in both panels). Results are representatives of 3 separate experiments.
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