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Blood, Vol. 112, Issue 5, 2156-2159, September 1, 2008 This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef A single nucleotide polymorphism at chromosome 2q21.3 (LCT –13910C>T) associates with clinical outcome after allogeneic hematopoietic stem cell transplantation Blood Hauser et al. 112: 2156 Supplemental materials for: Hauser et al Files in this Data Supplement: Figure S1. Overall survival in relation to donor LCT 13910C>T genotypes in different prognostic subgroups (JPG, 131 KB) - (A) patients age under vs. over 40 years, (B) AML vs. other diagnosis, (C) early vs. advanced stage of disease, (D) myeloablative vs. reduced intensity condititoning, (E) female donor and male recipient vs. other gender combinations, (F) HLA identical sibling vs. HLA matched unrelated or any mismatched donor. Figure S2. Influence of conditioning modality on TRM (JPG, 53 KB) - The LCT 13910 CC genotype was more common in donors of patients who recieved reduced intensity conditioning (Table 1). These figures are shown to rule out that improved survival with CC donors is confounded by less TRM due to more RIC. (In this cohort the main indication for RIC was higher age or comorbiditiy). (A) TRM in relation to conditioning therapy. Patients with a CC donor had a lower incidence of TRM with myeloablative conditioning (B) as well as with reduced intensity conditioning (C). Figure S3. Cumulative incidence of aGvHD grades II-IV in relation to (A) recipient and (B) donor LCT 13910 genotypes (JPG, 58.8 KB) - Cumulative incidence curves for aGVHD II-IV (until day +100) and a combined competing event (relapse or any death without aGvHD II-IV) are shown. P values were calculated with the Gray test. This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef

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