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Blood, Vol. 112, Issue 12, 4512-4522, December 1, 2008 This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code Blood Pimanda et al. 112: 4512 Supplemental materials for: Pimanda et al Files in this Data Supplement: Document 1. Supplemental materials and methods (PDF, 2.41 MB) Figure S1. Endoglin transcripts in paraffin sections of E7.5 and 8.5 embryos (with surrounding decidua) assayed by in situ hybridization (JPG, 65.6 KB) - E7.5 - Prominent signal is present in the highly vascular maternal uterus with weaker signal in the embryo (boxed in ×20 and magnified at ×40). E8.5- Transcripts are present in the developing heart tube/large vessels within the embryo (arrow at ×20) and blood cells within the yolk sac (dashed arrow at ×100). Figure S2. Flowcytometry plots of E12. 5 Fetal livers from transgenic (TG+ve) and non- transgenic embryos from a -8/P/LacZ transgenic line (L8072) × wild type cross (JPG, 19.4 KB) - The −8/P/LacZ transgene does not target FL hematopoietic cells. Figure S3. Quantitative PCR for Endoglin expression (JPG, 21.1 KB) - Levels were normalized to βactin expression and are plotted as a fold increase over BW 5147. Figure S4 (JPG, 52.7 KB) - Summary table comparing the degree of sequence conservation in non-coding regions between mouse/human (M/H) and mouse/opossum (M/O) species with chromatin accessibility of the Endoglin locus in HPC-7 blood progenitors and MS1 endothelial cells. This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef

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