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Blood, Vol. 113, Issue 13, 3059-3069, March 26, 2009 This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef Uniparental disomies, homozygous deletions, amplifications, and target genes in mantle cell lymphoma revealed by integrative high-resolution whole-genome profiling Blood Beà et al. 113: 3059 Supplemental materials for: Bea et al Files in this Data Supplement: Document 1. Supplemental materials and methods (PDF, 64 KB) Table S1. Characteristics of mantle cell lymphoma samples and summary of the number of alterations and uniparental disomies/trisomies (PDF, 42.5 KB) Table S2. Single genomic high-level DNA amplifications in mantle cell lymphoma and putative targets (PDF, 36 KB) Table S3. Enrichment of segmental duplications and copy number variants in mantle cell lymphoma breakpoints (PDF, 26.2 KB) Table S4. TP53 molecular analysis in mantle cell lymphoma (PDF, 66.1 KB) Figure S1. Representative diagrams showing the relationship between copy number changes and mRNA expression levels detected by quantitative PCR in mantle cell lymphoma (JPG, 33.3 KB) - (A) FAF1 gene (1p32.3), (B) SP100 gene (2q27) and (C) MOBKL2B gene (9p21.2). mRNA expression levels are represented in the y axis as continuous variables and the cut-off of 0.6 (low mRNA expression) is indicated by an horizontal line. The copy number changes are represented in three categories: homozygous deletion (HD), heterozygous deletion (DEL) and no deletion (WT). Samples with homozygous deletions and a subset of other samples with monoallelic deletion or no gene alteration showed absent or reduced expression levels of the three genes studied. This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef

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