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Blood, Vol. 113, Issue 11, 2535-2546, March 12, 2009
Zebrafish granulocyte colony-stimulating factor receptor signaling promotes myelopoiesis and myeloid cell migration
Blood Liongue et al.
113: 2535
Supplemental materials for: Liongue et al
Files in this Data Supplement:
- Figure S1. Sequence alignment of the extracellular domain of GCSFR (JPG, 123 KB)
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Conservation of residues showing identical (*), strong conservation (:), and weak conservation (.). Conserved motifs are indicated: cysteines and WSXWS are presented in pentagons.
- Figure S2. Sequence alignment of the extracellular domain of GCSFR (JPG, 41.5 KB)
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Quantitation of mpo+ cells in 96 hpf embryos previously injected with either scramMo or gcsfrMo1, with the mean (dashed red line), 95% confidence interval (red lines) indicated (p<0.01:**).
- Video 1. Migration of lyz::EGFP cells in embryos injected with scramMo during primitive myelopoiesis (MOV, 4.61 MB)
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Timecourse covering 21–26 hpf at 5 min intervals.
- Video 2. Migration of lyz::EGFP cells in embryos injected with gcsfrMo1 during primitive myelopoiesis (MOV, 4.48 MB)
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Timecourse covering 21–26 hpf at 5 min intervals.
- Video 3. Migration of lyz::EGFP cells in response to wounding in embryos injected with scramMo (MOV, 4.33 MB)
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Timecourse covering 15–165 min post wounding at 1 min intervals. The site of wounding is evident toward the bottom of the video.
- Video 4. Migration of lyz::EGFP cells in response to wounding in embryos injected with gcsfrMo1 (MOV, 3.89 MB)
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Timecourse covering 15–165 min post wounding at 1 min intervals. The site of wounding is evident toward the bottom of the video.
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