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Blood, Vol. 113, Issue 19, 4512-4520, May 7, 2009 This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia Blood French et al. 113: 4512 Supplemental materials for: French et al Files in this Data Supplement: Table S7. The correlation between the expression of IMPA2, PHLPP, and TYMS and MTXPG accumulation in leukemia cells differed by ALL subtype (PDF, 51.2 KB) Table S8. The expression of 10 genes was associated with methotrexate polyglutamate (MTXPG) accumulation after excluding patients (n=15) with extra copies of chromosome 10 from the analysis (PDF, 22.2 KB) - The expression of these genes was also associated with chromosome 10 copy number variation. Table S9. The correlation between the expression of the 10 significant genes on chromosome 10 and methotrexate polyglutamate accumulation in leukemia cells differed by ALL subtype (PDF, 54.4 KB) Table S10. The expression of 35 genes is significantly associated with MTXPG accumulation in both the patient leukemia cells (n=145) and the HapMap cell lines (n=176) (p<0.05) (PDF, 54.1 KB) Table S11. 35 inherited SNP genotypes (annotated to 11 genes) are significantly associated with MTXPG accumulation in the patient leukemia cells (n=144) and the HapMap cell lines (n=176) (p<0.01) (PDF, 69.5 KB) This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal Rights and Permissions Citing Articles Citing Articles via CrossRef

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