|
|
Blood, Vol. 113, Issue 23, 5938-5941, June 4, 2009
Tumor suppressor microRNAs are underrepresented in primary effusion lymphoma and Kaposi sarcoma
Blood O'Hara et al.
113: 5938
Supplemental materials for: O’Hara et al
Files in this Data Supplement:
- Table S1. Primary effusion lymphomas (PDF, 125 KB)
- Table S2. Additional changed genes (PDF, 121 KB)
- Figure S1. Shown are scatterplot matrix of the individual miRNA data for KSHV-infected (E1, L1, Cl1, Cl2) and uninfected (HUVEC.1 and HUVEC.2) cells (JPG, 693 KB)
-
Shown are the dCT values (normalized to U6). Reaction which did not yield any signal were filtered out, as it is not possible in this case to establish that loss of signal corresponded to absence of miRNA rather than assay failure. For each biological samples we measured three technical replicates. These are indicated by a., b., and c. E1 and L1 are biological replicates, i.e. two clones of one initially infected immortalized long-term EC culture (TIVE). Cl1 and Cl2 are true biological replicates, i.e. isolated of one initially infected immortalized EC culture (TIVE). HUVEC.1 and .2 are biological replicates, i.e. immortalized HUVEC cells from two different individual. Also shown (lower right) are the raw QPCR data (CT) for the mir-17-5 cluster, which is coregulated. Hence, the miRNAs levels for members of this cluster(mir-17-5, mir-18a, mir-19a, mir19b, mir-92, and mir-106a) should be correlated. This is evidenced by this scatterplot.
|
|
