Blood, Vol. 113, Issue 17, 4078-4085, April 23, 2009
Recombinant human activated protein C inhibits integrin-mediated neutrophil migration Blood Elphick et al. 113: 4078 Supplemental materials for: Elphick et al Files in this Data Supplement: Video 1. Time-lapse video microscopy of human neutrophils migration on FN toward micropipette containing 1 µM fMLP (1 second video=2.5 minute real time) (MOV, 489 KB) Video 2. Time-lapse video microscopy of human neutrophils migration on FN toward micropipette containing 1 µM fMLP in the presence of 10 µg/ml rhAPC (1 second video=2.5 minute real time) (MOV, 391 KB) Video 3. Time-lapse movie shows FRET image (highest red to lowest blue) of a hEPCR-mCFP and β1-mYFP transfected HEK293 cell (MOV, 425 KB) - Timescale of each frame is 10 sec. rhAPC (10 µg/ml) was added during the interval of the movie. Video 4. Time-lapse movie shows FRET image (highest red to lowest blue) of a hEPCR-mCFP and β1-mYFP transfected HEK293 cell (MOV, 429 KB) - Timescale of each frame is 10 sec. Gla less-APC (10 µg/ml) was added during the interval of the movie. Video 5. Time-lapse movie shows FRET image (highest red to lowest blue) of a hEPCR-mCFP and β1-mYFP transfected HEK293 cell (MOV, 568 KB) - Timescale of each frame is 10 sec. RGE-APC (10 µg/ml) was added during the interval of the movie.
Files in this Data Supplement:
