Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting
Blood Sanchez-Abarca et al.
10.1182/blood-2009-03-210393
Figure S2 (JPG, 303 KB)
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(A) (1) Whole signature of 7149 filtered genes disregulated in treated versus non-treated cells at 2 (a) and 4 (b) days and (2) signature of 170 genes with a null full discovery rate, represented through hierarchical clustering analysis. (2) Signature of 2189 differentially expressed genes with a FDR of 0,63% among treated versus non-treated cells at 2 (a) and 4 (b) days. (B) Partial gene regulatory network with genes involved in inmune response (blue semicircle) and cell cycle (yellow semicircle) comprising those described on Tables 1 and 2. Green to red background in selected genes maps to fold change at 4 days ranging from −4.72 to 6.04 respectively. Node label displays the gene symbol at NCBI GeneBank, and edge label represents the interaction support on APID database.