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Blood, 1 December 2005, Vol. 106, No. 12, pp. 3689. This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Search for Related Content Related Collections Blood Work Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  BLOOD WORK Dysplastic polychromatic "snowmoblast" A 69-year-old man was found to have pancytopenia. His hemoglobin level was 118 g/L with a normal mean corpuscular volume, white cell count 3.4 x 109/L, neutrophil count 1.7 x 109/L and platelet count 83 x 109/L. Blood smear showed dysplastic neutrophils, and the bone marrow aspirate confirmed myelodysplastic syndrome with 8% blasts (RAEB-1). He had trilineage dysplastic changes with prominent micromegakaryocytes and dyserythropoiesis. The nuclei of one of these dysplastic, polychromatic normoblasts took on the form of a snowman and is shown in the figure. Cytogenetic analysis revealed complex karyotype with rearrangements of chromosomes 7, 12, and 20, resulting in a partial deletion of 20q. Jiri Pavlu and Nicki Panoskaltsis, Imperial College London   [View Larger Version of this Image (120K GIF file)]   The above image was first published in the ASH IMAGE BANK, a reference and teaching tool that is continually updated with new atlas images and images of case studies. For more information or to contribute to the Image Bank, visit ashimagebank.hematologylibrary.org. CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this? This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Search for Related Content Related Collections Blood Work Social Bookmarking                   What's this?

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