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Blood, 1 September 2008, Vol. 112, No. 5, pp. 1581. This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Search for Related Content Related Collections Blood Work Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  BLOOD WORK Target cells and hemoglobinopathy View larger version (83K): [in this window] [in a new window]   A 52-year-old African-American man had a mild anemia (hemoglobin of 103 g/L) and target cells on the peripheral blood smear as shown. The white blood cell and platelet counts were normal. The referring physician assumed that a hemoglobinopathy could be present and a hemoglobin electrophoresis showed hemoglobin AC. He was referred for the hemoglobinopathy. Certainly, the appearance of targeted red cells raises the possibility of hemoglobinopathies (such as hemoglobin S, hemoglobin C, and hemoglobin E), as well as acquired disorders. However, the presence of hemoglobin C in this patient's electrophoresis does not provide the reason for his anemia. The hemoglobin C carrier state (AC) is not associated with anemia. When a complete evaluation was performed, the stool was hemoccult positive and an early colon carcinoma was found.     The above image was first published in the ASH IMAGE BANK, a reference and teaching tool that is continually updated with new atlas images and images of case studies. For more information or to contribute to the Image Bank, visit ashimagebank.hematologylibrary.org. CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this? This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Search for Related Content Related Collections Blood Work Social Bookmarking                   What's this?

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