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Blood, 1 June 2004, Vol. 103, No. 11, pp. 4003-4009. Prepublished online as a Blood First Edition Paper on February 12, 2004; DOI 10.1182/blood-2003-08-2744. This Article Full Text (PDF) All Versions of this Article: 2003-08-2744v1 103/11/4003    most recent Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Brenner, B. Search for Related Content PubMed PubMed Citation Articles by Brenner, B. Related Collections Related Letter in Blood Online Social Bookmarking                   What's this? Submitted August 12, 2003 Accepted January 19, 2004 Clinical Management of Thrombophilia Related Placental Vascular Complications Benjamin Brenner* Thrombosis and Haemostasis Unit, Rambam Medical Center, Haifa, Israel * Corresponding author; email: b_brenner{at}rambam.health.gov.il. Pregnancy is a hypercoagulable state with an increased thrombotic risk throughout gestation and the post-partum period. Women with thrombophilia may have a further increased risk of placental vascular complications, including, pregnancy loss pre-eclampsia, intrauterine growth restriction and placental abruption. Preliminary data suggest that maternal antithrombotic prophylaxis may result in improved gestational outcome. Randomized trials are underway and hopefully will optimize maternal and neonatal outcome. CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this? Related Letter in Blood Online: Early treatment with low-dose aspirin is effective for the prevention of preeclampsia and related complications in high-risk patients selected by the analysis of their historic risk factors Lionel Carbillon, Serge Uzan, and Benjamin Brenner Blood 2005 105: 902-903. [Full Text] [PDF] This article has been cited by other articles: S. M. Bates, I. A. Greer, I. Pabinger, S. Sofaer, and J. Hirsh Venous Thromboembolism, Thrombophilia, Antithrombotic Therapy, and Pregnancy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition) Chest, June 1, 2008; 133(6_suppl): 844S - 886S. [Abstract] [Full Text] [PDF] K. Ghosh, S. Shetty, S. Vora, and V. Salvi Successful Pregnancy Outcome in Women With Bad Obstetric History and Recurrent Fetal Loss Due to Thrombophilia: Effect of Unfractionated Heparin and Low--Molecular Weight Heparin Clinical and Applied Thrombosis/Hemostasis, April 1, 2008; 14(2): 174 - 179. [Abstract] [PDF] S. M. Bates Management of Pregnant Women with Thrombophilia or a History of Venous Thromboembolism Hematology, January 1, 2007; 2007(1): 143 - 150. [Abstract] [Full Text] [PDF] Y. Sato, H. Fujiwara, B.-X. Zeng, T. Higuchi, S. Yoshioka, and S. Fujii Platelet-derived soluble factors induce human extravillous trophoblast migration and differentiation: platelets are a possible regulator of trophoblast infiltration into maternal spiral arteries Blood, July 15, 2005; 106(2): 428 - 435. [Abstract] [Full Text] [PDF] L. Carbillon, S. Uzan, and B. Brenner Early treatment with low-dose aspirin is effective for the prevention of preeclampsia and related complications in high-risk patients selected by the analysis of their historic risk factors Blood, January 15, 2005; 105(2): 902 - 903. [Full Text] [PDF]

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