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This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by LEMPERT, N. Articles by SCHARFMAN, W. B. Search for Related Content PubMed PubMed Citation Articles by LEMPERT, N. Articles by SCHARFMAN, W. B. Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  Blood, 1963, Vol. 21, No. 2, pp. 213-220. © 1963 American Society of Hematology, Inc. Methods of Altering Nitrogen Mustard Toxicity in Dogs. I. Spleen and Mesenteric Artery Exclusion NEIL LEMPERT 1, ROBERT P. LEATHER 1, and WILLIAM B. SCHARFMAN 1 1 Department of Surgery, and the Subdepartment of Hematology in the Department of Medicine, Albany Medical College, Albany, N. Y. Forty-five dogs have been treated with varying dosages of nitrogen mustard. Nineteen of these dogs were subjected to cross-clamping of the splenic vessels prior to administration of the drug. No appreciable improvement in mortality or degree of marrow depression has been found with this technic. Exclusion of the spleen and small intestine has been found to be a practical and reliable method for protecting these organs from the effect of intravenous administration of nitrogen mustard. Submitted on April 30, 1962 Accepted on October 10, 1962 CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

	Copyright © 1963 by American Society of Hematology         Online ISSN: 1528-0020