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The presence of hemoglobin S and C Harlem in an individual in the United States

W Moo-Penn, K Bechtel, D Jue, MS Chan, G Hopkins, NJ Schneider, J Wright and RM Schmidt

The first reported case of hemoglobin S and C Harlem in an individual is described. The patient, a 35-yr-old female, had numerous crises during adolescence and early adulthood, but these occurred more infrequently as she grew older. Chemical evidence is presented for the characterization of both variant hemoglobins. The clinical course of this individual with Hb S in combination with Hb C Harlem appears to be similar to that for persons with sickle cell anemia.

Volume 46, Issue 3, pp. 363-367, 09/01/1975
Copyright © 1975 by The American Society of Hematology


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  Copyright © 1975 by American Society of Hematology         Online ISSN: 1528-0020