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Evidence for intracellular amyloid formation in myeloma
CR Kjeldsberg, HJ Eyre and H Totzke
Evidence for intracellular formation of amyloid fibrils in a patient with
kappa light-chain myeloma is described. Amyloid fibrils were seen as
intracytoplasmic inclusions within plasma cells, histiocytes, renal tubule
cells, and possibly in hepatocytes. Extracellular amyloid was also present.
The electron microscopic studies suggest that amyloid fibrils may form in
the Golgi apparatus and within lysosomes.
Volume 50,
Issue 3,
pp. 493-504,
09/01/1977
Copyright © 1977 by The American Society of Hematology
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