Interference of levamisole with inhibition of E-rosette formation by
Hodgkin's disease and systemic lupus erythematosus cytotoxic sera
GS Del Giacco, S Tognella, AL Leone, F Locci, P Cornaglia, A Sangiuolo and V Grifoni
A new system has been used to test the influence of levamisole on T- cell
function. Evidence has been produced that prior exposure to the drug
"protects" normal human peripheral blood lymphocytes from the inhibition
that cytotoxic sera from patients with Hodgkin's disease and systemic lupus
erythematosus exhibit on their E-rosette-forming capacity. Also, damage of
this T-cell function already induced by Hodgkin's sera may be partially
corrected.
Volume 53,
Issue 5,
pp. 1002-1006,
05/01/1979
Copyright © 1979 by The American Society of Hematology