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Genomic sequence and transcription start site for the human gamma- glutamyl carboxylase

SM Wu, DW Stafford, LD Frazier, YY Fu, KA High, K Chu, B Sanchez-Vega and J Solera

Department of Biology, University of North Carolina-Chapel Hill, 27599- 3280, USA.

The human gene for gamma-glutamyl carboxylase is 13 kb in length and contains 15 exons. Transcription starts at a cytosine 217 base pair upstream of the first codon. There are two major transcripts in all tissues examined. They are distinguished by the presence of an Alu sequence in the 3' nontranslated end of the longer species. Relative mRNA levels for 12 bovine tissues are presented.

Volume 89, Issue 11, pp. 4058-4062, 06/01/1997
Copyright © 1997 by The American Society of Hematology


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