|
|
 Previous Article | Table of Contents | Next Article 
Detection of Duffy antigen in the plasma membranes and caveolae of vascular
endothelial and epithelial cells of nonerythroid organs
A Chaudhuri, S Nielsen, ML Elkjaer, V Zbrzezna, F Fang and AO Pogo
Laboratory of Cell Biology, Lindsley F. Kimball Research Institute of the
New York Blood Center, NY 10021, USA.
The nonerythroid expression of the Duffy blood group protein (gp-Fy) was
confined to certain cell types. Immunocytochemistry studies of the kidney
showed gp-Fy in the endothelium of glomeruli, peritubular capillaries, vasa
recta, and the principal cells (epithelial) of collecting ducts. Gp-Fy was
also produced in the endothelial cells of large venules and epithelial
cells (type-I) of pulmonary alveoli. In the thyroid, only the endothelial
cells of capillaries produced gp-Fy. In the spleen, the endothelial cells
of capillaries, high endothelial venule, and sinusoids produced abundant
gp-Fy. Ultrastructural studies showed that apical and basolateral plasma
membrane domains, including caveolae, had gp-Fy. Immunoblot analysis showed
substantially less gp- Fy in nonerythroid cells than in erythrocytes.
Moreover, the analyzed nonerythroid organs of Duffy-negative individuals
did not produce more gp-Fy to compensate for the lack of this protein in
their erythrocytes. The nucleotide sequence and the size of kidney mRNA
from a Duffy- positive individual were the same as that of bone marrow. It
is assumed, therefore, that nonerythroid Duffy protein is the product of
the same gene as that of bone marrow. This notion is reinforced by the fact
that nonerythroid and erythroid gp-Fy have the same antigenic domains.
Volume 89,
Issue 2,
pp. 701-712,
01/15/1997
Copyright © 1997 by The American Society of Hematology
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati What's this?
This article has been cited by other articles:
|
|
|
|
 
C. S. McKimmie, A. R. Fraser, C. Hansell, L. Gutierrez, S. Philipsen, L. Connell, A. Rot, M. Kurowska-Stolarska, P. Carreno, M. Pruenster, et al.
Hemopoietic Cell Expression of the Chemokine Decoy Receptor D6 Is Dynamic and Regulated by GATA1
J. Immunol.,
September 1, 2008;
181(5):
3353 - 3363.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. W. Horton, Y. Yu, S. Zaja-Milatovic, R. M. Strieter, and A. Richmond
Opposing Roles of Murine Duffy Antigen Receptor for Chemokine and Murine CXC Chemokine Receptor-2 Receptors in Murine Melanoma Tumor Growth
Cancer Res.,
October 15, 2007;
67(20):
9791 - 9799.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Shen, R. Schuster, K. F. Stringer, S. E. Waltz, and A. B. Lentsch
The Duffy antigen/receptor for chemokines (DARC) regulates prostate tumor growth
FASEB J,
January 1, 2006;
20(1):
59 - 64.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Corral, J. Yelamos, D. Hernandez-Espinosa, Y. Monreal, R. Mota, I. Arcas, A. Minano, P. Parrilla, and V. Vicente
Role of Lipopolysaccharide and Cecal Ligation and Puncture on Blood Coagulation and Inflammation in Sensitive and Resistant Mice Models
Am. J. Pathol.,
April 1, 2005;
166(4):
1089 - 1098.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Bruhl, V. Vielhauer, M. Weiss, M. Mack, D. Schlondorff, and S. Segerer
Expression of DARC, CXCR3 and CCR5 in giant cell arteritis
Rheumatology,
March 1, 2005;
44(3):
309 - 313.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. S. Lee, C. W. Frevert, M. M. Wurfel, S. C. Peiper, V. A. Wong, K. K. Ballman, J. T. Ruzinski, J. S. Rhim, T. R. Martin, and R. B. Goodman
Duffy Antigen Facilitates Movement of Chemokine Across the Endothelium In Vitro and Promotes Neutrophil Transmigration In Vitro and In Vivo
J. Immunol.,
May 15, 2003;
170(10):
5244 - 5251.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. S. Lee, C. W. Frevert, D. R. Thorning, S. Segerer, C. E. Alpers, J.-P. Cartron, Y. Colin, V. A. Wong, T. R. Martin, and R. B. Goodman
Enhanced Expression of Duffy Antigen in the Lungs During Suppurative Pneumonia
J. Histochem. Cytochem.,
February 1, 2003;
51(2):
159 - 166.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Middleton, A. M. Patterson, L. Gardner, C. Schmutz, and B. A. Ashton
Leukocyte extravasation: chemokine transport and presentation by the endothelium
Blood,
December 1, 2002;
100(12):
3853 - 3860.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. J. Swardson-Olver, T. C. Dawson, R. C. Burnett, S. C. Peiper, N. Maeda, and A. C. Avery
Plasmodium yoelii uses the murine Duffy antigen receptor for chemokines as a receptor for normocyte invasion and an alternative receptor for reticulocyte invasion
Blood,
April 15, 2002;
99(8):
2677 - 2684.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Du, J. Luan, H. Liu, T. O. Daniel, S. Peiper, T. S. Chen, Y. Yu, L. W. Horton, L. B. Nanney, R. M. Strieter, et al.
Potential role for Duffy antigen chemokine-binding protein in angiogenesis and maintenance of homeostasis in response to stress
J. Leukoc. Biol.,
January 1, 2002;
71(1):
141 - 153.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. W. Hepburn, T. K. Hart, V. L. Horton, T. S. Sellers, L. P. Tobia, J. J. Urbanski, W. Shi, and C. B. Davis
Pharmacokinetics and Tissue Distribution of SB-251353, a Novel Human CXC Chemokine, after Intravenous Administration to Mice
J. Pharmacol. Exp. Ther.,
September 1, 2001;
298(3):
886 - 893.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
R. J. B. Nibbs, E. Kriehuber, P. D. Ponath, D. Parent, S. Qin, J. D. M. Campbell, A. Henderson, D. Kerjaschki, D. Maurer, G. J. Graham, et al.
The {beta}-Chemokine Receptor D6 Is Expressed by Lymphatic Endothelium and a Subset of Vascular Tumors
Am. J. Pathol.,
March 1, 2001;
158(3):
867 - 877.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Murdoch and A. Finn
Chemokine receptors and their role in inflammation and infectious diseases
Blood,
May 15, 2000;
95(10):
3032 - 3043.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Luo, A. Chaudhuri, V. Zbrzezna, Y. He, and A. O. Pogo
Deletion of the Murine Duffy Gene (Dfy) Reveals that the Duffy Receptor Is Functionally Redundant
Mol. Cell. Biol.,
May 1, 2000;
20(9):
3097 - 3101.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
P. M. Murphy, M. Baggiolini, I. F. Charo, C. A. Hebert, R. Horuk, K. Matsushima, L. H. Miller, J. J. Oppenheim, and C. A. Power
International Union of Pharmacology. XXII. Nomenclature for Chemokine Receptors
Pharmacol. Rev.,
March 1, 2000;
52(1):
145 - 176.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Gentilini, N. E. Kirschbaum, J. A. Augustine, R. H. Aster, and G. P. Visentin
Inhibition of Human Umbilical Vein Endothelial Cell Proliferation by the CXC Chemokine, Platelet Factor 4 (PF4), Is Associated With Impaired Downregulation of p21Cip1/WAF1
Blood,
January 1, 1999;
93(1):
25 - 33.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Tournamille, C. Le Van Kim, P. Gane, P. Y. Le Pennec, F. Roubinet, J. Babinet, J. P. Cartron, and Y. Colin
Arg89Cys Substitution Results in Very Low Membrane Expression of the Duffy Antigen/Receptor for Chemokines in Fyx Individuals
Blood,
September 15, 1998;
92(6):
2147 - 2156.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
I. Desbaillets, A.-C. Diserens, N. d. Tribolet, M.-F. Hamou, and E. G. V. Meir
Upregulation of Interleukin 8 by Oxygen-deprived Cells in Glioblastoma Suggests a Role in Leukocyte Activation, Chemotaxis, and Angiogenesis
J. Exp. Med.,
October 20, 1997;
186(8):
1201 - 1212.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Nielsen, A. Chaudhuri, A. O. Pogo;, T. J. Hadley, and S. C. Peiper
Which Are the Nonerythroid Cells That Constitutively Express the Duffy Antigen?
Blood,
October 15, 1997;
90(8):
3231 - 3232.
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Luo, A. Chaudhuri, K. R. Johnson, K. Neote, V. Zbrzezna, Y. He, and A. O. Pogo
Cloning, Characterization, and Mapping of a Murine Promiscuous Chemokine Receptor Gene: Homolog of the Human Duffy Gene
Genome Res.,
September 1, 1997;
7(9):
932 - 941.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Tournamille, C. L. Van Kim, P. Gane, D. Blanchard, A. E. Proudfoot, J. P. Cartron, and Y. Colin
Close Association of the First and Fourth Extracellular Domains of the Duffy Antigen/Receptor for Chemokines by a Disulfide Bond Is Required for Ligand Binding
J. Biol. Chem.,
June 27, 1997;
272(26):
16274 - 16280.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
